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GEMS Research Topics : ProteomicsKalyanasundaram, RamaswamyPhD, University of Calgary Research Interests Research Description Molecular basis of host evasion by pathogens; identify novel antigens for vaccine or drug development
Li, QingboPh.D., Iowa State University Research Interests Research Description My laboratory is interested in the role and the pathway of anaerobic respiration by M. tuberculosis for intracellular growth and persistence. Using proteomics approach, we are trying to identify and characterize the genes specific for the microaerobic or anaerobic metabolism of M. tuberculosis. We use metabolic labeling methods to quantify the details of protein synthesis by M. tuberculosis grown within macrophages. We are also involved in elucidating the T cell antigens synthesized by intracellular mycobacteria. This knowledge is being used for understanding the mechanism of tuberculosis latency.
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