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GEMS Research Topics : MicrobiologyChakrabarty, AnandaPh.D, University of Calcutta Research Interests Research Description Microorganisms and cancer; interaction of microbial redox proteins with the tumor suppressor protein p53; development of anticancer drugs from microbial sources.
Cook, JamesMD, Baylor University Research Interests Research Description Viral gene control of cellular response to injury. (Cellular immune response to viral infection) Immunopathogenesis and drug discovery for Anthrax
Federle, MichaelPh.D., Emory University Research Interests Research Description Cell-cell signaling in bacteria, a process termed Quorum Sensing. We are identifying the chemical signals and signaling pathways used by bacteria to control population-wide behaviors, which include their ability to cause disease in humans. Eventually we hope to discover means by which we can interfere with bacteria's communication processes and ultimately alter the progression of bacterial infections.
Hecht, GailMD, Loyola University Research Interests Research Description Mechanisms of effects of enteropathogenic and enterohemorrhagic E. coli on host intestinal epithelial cell functions including tight junction permeability, the inflammatory response, and ion transport.
Kenney, LindaPhD, University of Pennsylvania Research Interests Research Description Two-component signal transduction; Regulation of Salmonella pathogenicity Island 2 gene expression; Regulation of outer membrane proteins by EnvZ/OmpR
Li, QingboPh.D., Iowa State University Research Interests Research Description My laboratory is interested in the role and the pathway of anaerobic respiration by M. tuberculosis for intracellular growth and persistence. Using proteomics approach, we are trying to identify and characterize the genes specific for the microaerobic or anaerobic metabolism of M. tuberculosis. We use metabolic labeling methods to quantify the details of protein synthesis by M. tuberculosis grown within macrophages. We are also involved in elucidating the T cell antigens synthesized by intracellular mycobacteria. This knowledge is being used for understanding the mechanism of tuberculosis latency.
Marucha, PhillipPhD, University of Connecticut Research Interests Research Description Stress-Impaired Oxygen Dependent Transcription in Wounds; Distress, Saliva Composition, and Saliva Functions; Interdisciplinary Research in Cancer from an Oral Perspective; Modulation of Inflammation by Stress and Social Factors; Mechanisms of Neuroendocrine Regulation of Wound Healing During Aging
Matsumura, PhilipPh.D., Rochester University Research Interests Research Description Mechanisms of signal transduction in bacterial chemotaxis. By combining genetics with biochemistry and structural chemistry, we are defining the detailed protein-protein interactions that constitute the biochemical pathway of signal transduction.
Tao, LinD.D.S., Ph.D., University of Connecticut Research Interests Research Description Microbial genetics of streptococci and lactobacilli
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