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GEMS Research Topics : Host-Pathogen BiologyChen, ZhengM.D., Ph.D., Peking Union Medical College Research Interests Research Description Fundamental immunology of antigen- specific gamma delta T cells; gamma delta T cell-based immunotherapeutics; MHC class I-restricted CD8+ CTL responses in TB and AIDS; Vaccine development for TB and AIDS; Immunopathogenesis in AIDS virus- mycobacterial coinfection; T cell- targeted biodefense.
Chishti, AtharPh.D., University of Melbourne, Australia Research Interests Research Description Assembly and Regulation of the Cytoskeleton. Function of MAGUKs (membrane associated guanylate kinases); role of calpains in platelet function; mechanisms of malaria parasite pathogenesis in red blood cells; cell proliferation and tumor suppression pathways.
Cook, JamesMD, Baylor University Research Interests Research Description Viral gene control of cellular response to injury. (Cellular immune response to viral infection) Immunopathogenesis and drug discovery for Anthrax
Federle, MichaelPh.D., Emory University Research Interests Research Description Cell-cell signaling in bacteria, a process termed Quorum Sensing. We are identifying the chemical signals and signaling pathways used by bacteria to control population-wide behaviors, which include their ability to cause disease in humans. Eventually we hope to discover means by which we can interfere with bacteria's communication processes and ultimately alter the progression of bacterial infections.
Freitag, NancyPhD, University of California at Los Angeles Research Interests Research Description
He, BinPhD, Purdue University Research Interests Research Description Biology and pathogenesis of virus infection; virus-host interactions; virus strategies to escape host response
Hecht, GailMD, Loyola University Research Interests Research Description Mechanisms of effects of enteropathogenic and enterohemorrhagic E. coli on host intestinal epithelial cell functions including tight junction permeability, the inflammatory response, and ion transport.
Kalyanasundaram, RamaswamyPhD, University of Calgary Research Interests Research Description Molecular basis of host evasion by pathogens; identify novel antigens for vaccine or drug development
Lipton, HowardM.D., University of Nebraska Research Interests Research Description Mechanisms of viral persistence and immunopathogenesis of the picornavirus, Theiler's virus, in the central nervous system of mice
McLachlan, AlanPh.D., University of Aberdeen, Scotland Research Interests Research Description Regulation of hepatitis B virus transcription and replication
Shukla, DeepakPh.D., University of Illinois at Chicago Research Interests Research Description Molecular basis for viral entry; mouse model for ocular herpes
Tao, LinD.D.S., Ph.D., University of Connecticut Research Interests Research Description Microbial genetics of streptococci and lactobacilli
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