GEMS Research Topics : Gene RegulationAckerman, StevenPh.D., McGill University Research Interests Research Description Transcriptional mechanisms that regulate blood cell (granulocyte/eosinophil) lineage-specific development and gene expression during hematopoiesis. Cellular, molecular and immunobiology of the eosinophil granulocyte, focusing on pro-inflammatory effector functions in the pathogenesis of asthma and other allergic diseases such as eosinophilic esophagitis - mechanisms of eosinophil-mediated tissue damage, repair-remodeling and fibrosis are being investigated.
de Lanerolle, PrimalPhD, University of California, San Diego Research Interests Research Description The cytoskeleton in signal transduction; Molecular motors in the nucleus
Diekwisch, ThomasDDS, Ph.D. (sci), Ph.D. (phil), Philipps-University of Marburg, West Germany Research Interests Research Description Developmental, molecular, and evolutionary biology of tooth enamel and periodontium
Frolov, MaximPh.D, Moscow State University Research Interests Research Description The role of E2F and pRB in normal and oncogenic proliferation. The function of the novel Hippo tumor suppressor pathway in Drosophila.
Fukai, TohruMD, PhD, Kyushu University, Fukuoka, Japan Research Interests Research Description To determine the role of oxidative stress and copper transport system in cardiovascular disease.
Gartel, AndreiPh.D., Institute of Virology, Moscow, Russia Research Interests Research Description Regulation of CDK inhibitor p21 in normal and cancer cells, Anticancer drugs that target antiapoptotic pathways
Ikegaki, NaohikoPhD, University of Pennsylvania Research Interests Research Description Biology and therapeutic approaches of neuroblastoma; functions of MYCN, EPH receptors, and ephrims in neuroblastoma
Kennedy, JohnPhD, Medical College of Virginia Research Interests Research Description Molecular Mechanisms controlling expression of metabolic genes during cardiac and skeletal muscle adaptation.
Kenney, LindaPhD, University of Pennsylvania Research Interests Research Description Two-component signal transduction; Regulation of Salmonella pathogenicity Island 2 gene expression; Regulation of outer membrane proteins by EnvZ/OmpR
Kenter, AmyPhD, Yeshiva (Albert Einstein College of Medicine) Research Interests Research Description Genetic mechanisms of immunoglobulin gene recombination; DNA-binding proteins; B cell specific nucleic enzymes; plasmid recombination assays.
Matsumura, PhilipPh.D., Rochester University Research Interests Research Description Mechanisms of signal transduction in bacterial chemotaxis. By combining genetics with biochemistry and structural chemistry, we are defining the detailed protein-protein interactions that constitute the biochemical pathway of signal transduction.
McLachlan, AlanPh.D., University of Aberdeen, Scotland Research Interests Research Description Regulation of hepatitis B virus transcription and replication
Mirkin, SergeiPh.D., Institute of Molecular Genetics, Russian Academy of Sciences Research Interests Research Description Genome Structure and Functioning; Molecular Mechanisms of Genetic Processes; Structure and Stability of DNA
Mokyr, MargalitPh.D., Rush University Research Interests Research Description Molecular mechanism of immunopotentiation by anticancer drugs
Raychaudhuri, PradipPh.D., Albert Einstein College of Medicine Research Interests Research Description We use both mammalian and yeast genetics to study DNA damage response, cell cycle checkpoints and tumor suppression
Walden, WilliamPh.D., Washington University Research Interests Research Description Mechanisms of iron regulation and FeS cluster assembly; translational mechanisms and regulation.
Yue, BeatricePh.D. Research Interests Research Description Biochemical and molecular basis of keratoconus; studies of glaucoma genes.
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