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GEMS Research Topics : Cell and Membrane BiologyArt, JonathanPh.D., University of Chicago Research Interests Research Description Biophysical properties of Cochlear Hair Cells
Bongarzone, Ernesto R.PhD, University of Buenos Aires Research Interests Research Description Molecular and cellular mechanisms controlling endogenous remyelination; improving myelin repair with stem cell transplantation
Chishti, AtharPh.D., University of Melbourne, Australia Research Interests Research Description Assembly and Regulation of the Cytoskeleton. Function of MAGUKs (membrane associated guanylate kinases); role of calpains in platelet function; mechanisms of malaria parasite pathogenesis in red blood cells; cell proliferation and tumor suppression pathways.
Colley, KarenPh.D., Washington University Research Interests Research Description Control of glycoprotein biosynthesis during development and disease; mechanisms of Golgi protein trafficking and localization.
García-Martínez, JesúsM.D., Ph.D., CINVESTAV, México Research Interests Research Description Signal transduction in striated muscle. Excitation-contraction coupling and gene expression in skeletal and cardiac muscle.
Hay, NissimPhD, Weizmann Institute, Israel Research Interests Research Description Analyses of apoptosis, cell cycle control, metabolism, and life span mediated by growth factors, at the cellular and organismal levels.
Hudson, RandallPh.D., Washington State University Research Interests Research Description
Kaplan, JackPhD, London University Research Interests Research Description Molecular characterization of P-type ATPases (Ion Pumps): structure- function relations, synthesis, assembly and trafficking. Mechanisms and Regulation of Copper transport in Human Cells.
Mehta, DollyPh.D., Delhi University, India Research Interests Research Description Rho regulation of actin polymerization.
O'Bryan, John P.Ph.D., University of North Carolina at Chapel Hill Research Interests Research Description The research in the lab is focused on the role of scaffolding proteins in the regulation of signal transduction pathways, protein ubiquitylation, trafficking and endocytosis.
Prabhakar, BellurPh.D., Johns Hopkins University Research Interests Research Description Role of regulatory T cells in autoimmunity, Molecular mechanisms of actions of IG20 splice variants that can promote either apoptosis or cell- growth. Therapeutic interventions against SARS.
Tiruppathi, ChinnaswamyPh.D., University of Madras Research Interests Research Description Our primary research interest is to study the molecular mechanism that regulates vascular inflammation. Pro- inflammatory mediator thrombin induces vascular inflammation by cleaving the endothelial cell surface protease activated receptor-1 (PAR-1). PAR-1 activation causes vascular leakage and neutrophil adhesion-mediated vascular injury. Ca2+ signaling plays an important role in the mechanism of thrombin-induced vascular injury. Currently, we are investigating how thrombin increases intracellular Ca2+ by opening plasma membrane transient receptor potential channels expressed in endothelial cells. In addition, we are also investigating the role of Ca2+ signaling in the mechanism of nuclear factor ?B (NF-?B) activation- dependent expression of inflammatory genes in endothelial cells.
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