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GEMS Research Topics : Bio-imagingArt, JonathanPh.D., University of Chicago Research Interests Research Description Biophysical properties of Cochlear Hair Cells
Fall, ChrisPh.D., University of Virginia Research Interests Research Description Computational and experimental approaches for understanding the neuromodulation of cortical activity patterns; computational and experimental cell biology of intracellular Ca2+ signaling and related second messengers; mechanisms of cell death in neurodegenerative disease.
Li, QingboPh.D., Iowa State University Research Interests Research Description My laboratory is interested in the role and the pathway of anaerobic respiration by M. tuberculosis for intracellular growth and persistence. Using proteomics approach, we are trying to identify and characterize the genes specific for the microaerobic or anaerobic metabolism of M. tuberculosis. We use metabolic labeling methods to quantify the details of protein synthesis by M. tuberculosis grown within macrophages. We are also involved in elucidating the T cell antigens synthesized by intracellular mycobacteria. This knowledge is being used for understanding the mechanism of tuberculosis latency.
Little, DeborahPh.D., Brandeis University Research Interests Research Description Ageing, dementia and neuroimaging
Minshall, RichardPh.D., University of Illinois at Chicago Research Interests Research Description Investigates signaling mechanisms regulating paracellular and transcellular permeability of the endothelium to macromolecules and therapeutic agents. Confocal microscopy, physiological, molecular, cellular, and biochemical approaches are used to study trafficking of caveolae, organization and remodeling of the cytoskeleton and cell-cell junctions, protein and fluid permeability, and signaling modules that regulate endothelial cell function. Current projects focus on 1) the signaling molecules that regulate caveolae-mediated endocytosis and transcytosis, 2) delivery of therapeutic agents across the vascular barrier, and 3) the role of caveolae in inflammation-induced increase in permeability.
Shahidi, MahnazPh.D. Research Interests Research Description Development of optical imaging systems for quantitative assesment of eye diseases.
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