GEMS Faculty

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Tang, Xao X.

PhD, University of Pennsylvania
Assistant Professor of Anatomy and Cell Biology
xaotang@uic.edu

Research Interests
Cancer Biology , Neuroscience

Research Description

Favorable neuroblastoma genes and molecular therapeutics of neuroblastoma

Tao, Lin

D.D.S., Ph.D., University of Connecticut
Associate Professor, Microbiology and Immunology,
ltao@uic.edu 312-355-4077

Research Interests
Host-Pathogen Biology , Microbiology

Research Description

Microbial genetics of streptococci and lactobacilli

Tiruppathi, Chinnaswamy

Ph.D., University of Madras
Associate Professor of Pharmacology
tiruc@uic.edu 312-355-0249

Research Interests
Vascular Biology , Cell and Membrane Biology

Research Description

Our primary research interest is to study the molecular mechanism that regulates vascular inflammation. Pro- inflammatory mediator thrombin induces vascular inflammation by cleaving the endothelial cell surface protease activated receptor-1 (PAR-1). PAR-1 activation causes vascular leakage and neutrophil adhesion-mediated vascular injury. Ca2+ signaling plays an important role in the mechanism of thrombin-induced vascular injury. Currently, we are investigating how thrombin increases intracellular Ca2+ by opening plasma membrane transient receptor potential channels expressed in endothelial cells. In addition, we are also investigating the role of Ca2+ signaling in the mechanism of nuclear factor ?B (NF-?B) activation- dependent expression of inflammatory genes in endothelial cells.

Tyner, Angela

Ph.D. University of Chicago
Professor of Biochemistry and Molecular Genetics
atyner@uic.edu 312-996-7964

Research Interests
Signal Transduction and Cell Signaling , Cell cycle & Apoptosis, Cancer Biology

Research Description

Regulation of epithelial cell differentiation; Cell cycle regulation in regenerating tissues; Cancer