Graduate Education in Medical Sciences at University of Chicago





GEMS Faculty

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Malik, A.B.

Ph.D., University of Toronto, Canada
Distinguished Professor and Head, Department of Pharmacology
abmalik@uic.edu  312-996-7635

Research Interests
Vascular Biology , Lung Biology, Signal Transduction and Cell Signaling

Research Description

Gene regulation in endothelial cells; expression of adhesion molecules and their transcriptional regulation; regulation of endothelial transport; assembly of adherens junctions; function of caveolin-1 in endothelial cells.

 

Marucha, Phillip

PhD, University of Connecticut
Professor of Periodontics, Microbiology and Immunology
marucha@uic.edu  312-413-5902

Research Interests
Immunology , Microbiology

Research Description

Stress-Impaired Oxygen Dependent Transcription in Wounds; Distress, Saliva Composition, and Saliva Functions; Interdisciplinary Research in Cancer from an Oral Perspective; Modulation of Inflammation by Stress and Social Factors; Mechanisms of Neuroendocrine Regulation of Wound Healing During Aging

 

Matsumura, Philip

Ph.D., Rochester University
Professor, Microbiology and Immunology
Philip.Matsumura@uic  312-996-2286

Research Interests
Microbiology , Signal Transduction and Cell Signaling, Gene regulation

Research Description

Mechanisms of signal transduction in bacterial chemotaxis. By combining genetics with biochemistry and structural chemistry, we are defining the detailed protein-protein interactions that constitute the biochemical pathway of signal transduction.

 

McLachlan, Alan

Ph.D., University of Aberdeen, Scotland
Professor, Medicine, Microbiology and Immunology
mclach@uic.edu  312-355-0211

Research Interests
Virology , Gene Regulation, Host-Pathogen Biology

Research Description

Regulation of hepatitis B virus transcription and replication

 

Mehta, Dolly

Ph.D., Delhi University, India
Assistant Professor of Pharmacology
dmehta@uic.edu  312-355-0236

Research Interests
Vascular Biology , Signal Transduction and Cell Signaling, Cell and Membrane Biology

Research Description

Rho regulation of actin polymerization.

 

Merrill, Brad

Ph.D., University of California, San Diego
Assistant Professor of Biochemistry and Molecular Genetics
merrillb@uic.edu  312-996-0346

Research Interests
Cancer Biology , Development, Stem Cell Biology

Research Description

We examine how transcription factors determine cell fates, with a particular focus on effects on stem cells and during carcinogenesis.

 

Minshall, Richard

Ph.D., University of Illinois at Chicago
Associate Professor of Pharmacology and Anesthesiology
rminsh@uic.edu  312-996-1655

Research Interests
Vascular Biology , Signal Transduction and Cell Signaling, Bio-imaging

Research Description

Investigates signaling mechanisms regulating paracellular and transcellular permeability of the endothelium to macromolecules and therapeutic agents.  Confocal microscopy, physiological, molecular, cellular, and biochemical approaches are used to study trafficking of caveolae, organization and remodeling of the cytoskeleton and cell-cell junctions, protein and fluid permeability, and signaling modules that regulate endothelial cell function.  Current projects focus on 1) the signaling molecules that regulate caveolae-mediated endocytosis and transcytosis, 2) delivery of therapeutic agents across the vascular barrier, and 3) the role of caveolae in inflammation-induced increase in permeability.

 

Mirkin, Sergei

Ph.D., Institute of Molecular Genetics, Russian Academy of Sciences
Professor of Biochemistry and Molecular Genetics
mirkin@uic.edu  312-996-9610

Research Interests
Gene Regulation , Biochemistry, Genetics

Research Description

Genome Structure and Functioning; Molecular Mechanisms of Genetic Processes; Structure and Stability of DNA

 

Mokyr, Margalit

Ph.D., Rush University
Professor of Biochemistry and Molecular Genetics
mokyr@uic.edu  312-996-2343

Research Interests
Immunology , Cancer Biology, Gene regulation

Research Description

Molecular mechanism of immunopotentiation by anticancer drugs