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GEMS FacultyA | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z LaDu, Mary JoPhD, University of Illinois at Chicago Research Interests Research Description Identify the role of apoE:A-Beta complexes and apoE receptors in A- beta ?induced neurotoxicity
Lam, StephenPhD, University of Toronto Research Interests Research Description Platelet adhesive functions in hemostasis and thrombosis; structure- function relationship of integrin alpha IIb?3.
Lau, LesterPh.D., Cornell University Research Interests Research Description Tumor Angiogenesis, Cardiovascular Development, Extracellular Matrix Signaling, Aging
Lavie, ArnonPh.D., Brandeis University Research Interests Research Description Structure-based design of novel therapeutic agents by prodrug development and enzyme modifications. X-ray crystallographic structure determination of enzymes involved in prodrug activation.
Lazarov, OrlyPh.D., Weizmann Institute of Science Research Interests Research Description Cellular and molecular mechanisms underlying Alzheimer's disease; Misregulation of neurogenic processes in the AD brain; Neurogenesis and stem cell-based therapeutic approaches.
Le Breton, GuyPh.D., University of Chicago Research Interests Research Description Fundamental mechanisms and signal transduction processes involved in platelet activation and inhibition.
Lewandowski, E. DouglasPh.D., University of Texas Southwestern Medical School Research Interests Research Description Research explores the metabolic basis of cardiac dysfunction in heart disease. Focus is on metabolic flux regulation via enzyme expression using a novel combination of molecular techniques and magnetic resonance spectroscopy of the intact heart. Gene therapy, through the in vivo delivery of cardiac-specific, adenoviral constructs, enables the manipulation of enzyme expression and activity in animal models of heart disease. The program develops new methods for nuclear magnetic resonance (NMR) to detect intracellular transport rates and chemical reactions in intact, functioning tissues using new approaches for stable isotope kinetics in whole organs.
Li, JianxunPh.D., City University of New York Research Interests Research Description Molecular Mechanism of Immune Cell Activation.
Li, QingboPh.D., Iowa State University Research Interests Research Description My laboratory is interested in the role and the pathway of anaerobic respiration by M. tuberculosis for intracellular growth and persistence. Using proteomics approach, we are trying to identify and characterize the genes specific for the microaerobic or anaerobic metabolism of M. tuberculosis. We use metabolic labeling methods to quantify the details of protein synthesis by M. tuberculosis grown within macrophages. We are also involved in elucidating the T cell antigens synthesized by intracellular mycobacteria. This knowledge is being used for understanding the mechanism of tuberculosis latency.
Lipton, HowardM.D., University of Nebraska Research Interests Research Description Mechanisms of viral persistence and immunopathogenesis of the picornavirus, Theiler's virus, in the central nervous system of mice
Little, DeborahPh.D., Brandeis University Research Interests Research Description Ageing, dementia and neuroimaging
Lysakowski, AnnaPh.D., University of Illinois at Chicago Research Interests Research Description Ionic composition and synaptic innervation of hair cells. Efferent innervation of the vestibular periphery
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